MOLECULAR GRAPHICS LINKS
FOR STUDY& REVIEW
|
| Date | Topic | Instructor |
| 8/30 | Introduction | Wilkinson |
| 8/31 | Preview: Chemical Equilibria | Jones & Russell |
| 9/1 | Thermodynamics and Equilibrium | Wilkinson |
| 9/3 | Protein Properties and Purification
|
Wilkinson |
| 9/6 | Labor Day - No Class | --- |
| 9/7 | Preview: Amino Acids and Peptide Bonds Advanced Topic: Computation and Graphical Methods
| Jones & Haremen Gernert Gernert |
| 9/8 | Primary Structure and peptide chains | Hodel |
| 9/10 | Secondary and Tertiary Structure | Hodel |
| 9/13 | Protein Folding and Domain Structure | Hodel |
| 9/14 | Preview: Chemical Kinetics Advanced Topic 1: Protein Folding Advanced Topic 2: Prions and Inclusion Body Disease |
Jones & Russell Hodel Chernoff |
| 9/15 | Hemoglobin Structure and Function | Hodel |
| 9/17 | MM and the Steady State Approximation | Edmondson |
| 9/20 | Two Substrate Reactions and Inhibitors | Edmondson |
| 9/21 | Preview: Nucleosides and Nucleotides Advanced Topic 1: Enzyme Inhibitors as Drugs Advanced Topic 2: Receptors and Transport Processes |
Benki & Herreman Edmondson Traynelis |
| 9/22 | Specificity and Rate Enhancement | Edmondson |
| 9/24 | Selected Enzyme Mechanisms | Edmondson |
| 9/27 | Structural Properties of Nucleic Acids | Doetsch |
| 9/28 | Examination 1 | --- |
| 9/29 | Nucleic Acid Manipulation and Analysis | Doetsch |
| 10/1 | DNA Sequencing | Doetsch |
| 10/4 | Topology, Chromatin Structure | Doetsch |
| 10/5 | Preview: Carbohydrates and Lipids Advanced Topic 1: DNA Damage, Repair, and Cancer Advanced Topic 2: Specialized DNA Sequences |
Benki & Harreman Doetsch Vertino |
| 10/6 | DNA Repair | Doetsch |
| 10/8 | Carbohydrate Structure and Properties
|
Stevens |
| 10/11 | Fall Break - No Class | --- |
| 10/12 | Fall Break - No Class | --- |
| 10/13 | Carbohydrate Structure and Properties
|
Stevens |
| 10/15 | Lipid Structure and Properties
|
Stevens |
| 10/18 | Membranes, Fluid Mosaic Model
|
Stevens |
| 10/19 | Preview: Replication Advanced Topic 1: Membrane Domains and Microdomains Advanced Topic 2: Lipid Homeostasis and Trafficking |
Russell & Jones Stevens Nichols |
| 10/20 | Biological Membranes and Lipoproteins | Stevens |
| 10/22 | Enzymes of DNA Metabolism | Shadel |
| 10/25 | Prokaryotic Replication | Shadel |
| 10/26 | Preview: Recomb./Repair Advanced Topic 1: p53 and Timing of Replication Advanced Topic 2: Recombination and Immunoglobulin |
Russell&Jones&Benki&Harreman Van Meir Seide |
| 10/27 | Eukaryotic Replication | Shadel |
| 10/29 | Recombination | Shadel |
| 11/1 | Recombination | Shadel |
| 11/2 | Examination 2 | --- |
| 11/3 | Biochemical Definition of the Gene | Reines |
| 11/5 | Functions of RNA and Polymerases | Reines |
| 11/8 | Prokaryotic Gene Expression | Reines |
| 11/9 | Preview: Bacteria and Phage Advanced Topic 1: DNA Binding Proteins Advanced Topic 2: Processing of mRNA's |
Benki & Jones Price Reines |
| 11/10 | Eukaryotic Gene Expression | Reines |
| 11/12 | The Ribosome
|
Warren |
| 11/15 | Initiation | Warren |
| 11/16 | Preview: Molecular Genetics I Advanced Topic 1: Nuclear Transport Advanced Topic 2: Translational Control |
Benki & Harreman Corbett Hagadorn |
| 11/17 | Elongation/Termination | Warren |
| 11/19 | Genome Anatomy and Gene Mapping | Fridovich-Keil |
| 11/22 | Recombinant DNA I | Fridovich-Keil |
| 11/23 | Preview: Molecular Genetics II Advanced Topic 1: Positional Cloning Advanced Topic 2: Transgenic Animals |
Benki & Harreman Fridovich-Keil MacGregor |
| 11/24 | Thanksgiving Holiday - No Class | --- |
| 11/26 | Thanksgiving Holiday - No Class | --- |
| 11/29 | Recombinant DNA II | Fridovich-Keil |
| 11/30 | Preview: General Review Advanced Topic 1: Combinatorial Methods Advanced Topic 2: Gene Therapy |
All TAs Hodel Pavlath |
| 12/1 | Cloning, knockouts, and Transgenics | Fridovich-Keil |
| 12/3 | Thought Exercise in Cloning | Fridovich-Keil |
| 12/6 | Nothing - No Class | --- |
| 12/7 | Examination 3 | --- |